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Gene ENSMUSG00000005871 (Apc)
Chromosomal location
Chr 18: 34380638 - 34479735 (+)
Description
adenomatosis polyposis coli Gene [Source:MGI Symbol;Acc:MGI:88039]
RefSeq_dna
NM_007462 
RefSeq_peptide
NP_031488.2 
UniGene
Mm.470430 Mm.384171 
MGI
MGI:88039 
Uniprot/SWISSPROT
Q61315 
Uniprot/SPTREMBL
Q8C493 Q8C9I9 Q3UQT2 B2RUG9 Q8BNP7 Q8BRD8 
Human Ortholog
ENSG00000134982 (APC)
Omim 135290 - DESMOID DISEASE, HEREDITARY  155255 - MEDULLOBLASTOMA  175100 - ADENOMATOUS POLYPOSIS OF THE COLON  276300 - MISMATCH REPAIR CANCER SYNDROME  
UniTrap UNI2975
Vector Insertion
Chr 18: 34380637 - 34380931
Public Clones AB0046 (sanger)
Private Clones not available
Severity of mutation (?) Insertion after 0% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI18214
Vector Insertion
Chr 18: 34380931 - 34420658
Public Clones (sanger) E055B10 (ggtc) E125A02 (ggtc) IST11644C12 (tigm) IST14540B9 (tigm)
IST11272F11 (tigm) IST14962H11 (tigm) IST14264D9 (tigm) IST14648A4 (tigm)
IST14648A5 (tigm)
Private Clones OST427365 (lexicon) OST427118 (lexicon) OST426730 (lexicon) OST382068 (lexicon)
OST360255 (lexicon) OST301926 (lexicon) OST291741 (lexicon) OST166517 (lexicon)
OST166477 (lexicon) OST52435 (lexicon) OST33788 (lexicon)
Severity of mutation (?) Insertion after 0% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI22999
Vector Insertion
Chr 18: 34428034 - 34428709
Public Clones not available
Private Clones OST279266 (lexicon)
Severity of mutation (?) Insertion after 3% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI7476
Vector Insertion
Chr 18: 34436332 - 34438922
Public Clones RRN319 (baygenomics) RRR800 (baygenomics)
Private Clones not available
Severity of mutation (?) Insertion after 8% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI10387
Vector Insertion
Chr 18: 34439007 - 34449009
Public Clones XA018 (baygenomics)
Private Clones not available
Severity of mutation (?) Insertion after 9% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI36424
Vector Insertion
Chr 18: 34449845 - 34455684
Public Clones (sanger) IST12622E6 (tigm)
Private Clones not available
Severity of mutation (?) Insertion after 9% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI33575
Vector Insertion
Chr 18: 34466034 - 34470346
Public Clones IST11575B8 (tigm) IST11177C12 (tigm) IST13646C10 (tigm) IST10099E4 (tigm)
Private Clones not available
Severity of mutation (?) Insertion after 20% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

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