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Gene ENSMUSG00000019969 (Psen1)
Chromosomal location
Chr 12: 85029152 - 85076149 (+)
Description
presenilin 1 Gene [Source:MGI Symbol;Acc:MGI:1202717]
RefSeq_dna
NM_008943 
RefSeq_peptide
NP_032969.1 
UniGene
Mm.998 
MGI
MGI:1202717 
Uniprot/SWISSPROT
P49769 
Uniprot/SPTREMBL
Q3TDW2 Q3UYK2 
Human Ortholog
ENSG00000080815 (PSEN1)
Omim 600274 - FRONTOTEMPORAL DEMENTIA  607822 - ALZHEIMER DISEASE 3  
UniTrap UNI32909
Vector Insertion
Chr 12: 85029884 - 85040304
Public Clones IST15057B4 (tigm) IST15057C3 (tigm)
Private Clones not available
Severity of mutation (?) Insertion after 0% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI2394
Vector Insertion
Chr 12: 85040602 - 85053253
Public Clones AD0063 (sanger) AT0292 (sanger) (ggtc)
Private Clones not available
Severity of mutation (?) Insertion after 6% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI27369
Vector Insertion
Chr 12: 85053505 - 85055713
Public Clones not available
Private Clones OST61485 (lexicon) OST32594 (lexicon)
Severity of mutation (?) Insertion after 24% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

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