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Gene ENSMUSG00000024068 (Spast)
Chromosomal location
Chr 17: 74738353 - 74790453 (+)
Description
spastin Gene [Source:MGI Symbol;Acc:MGI:1858896]
RefSeq_peptide
NP_058658.1 
UniGene
Mm.19804 Mm.469676 
MGI
MGI:1858896 
Uniprot/SWISSPROT
Q9QYY8 
Human Ortholog
ENSG00000021574 (SPAST)
Omim 182601 - SPASTIC PARAPLEGIA 4, AUTOSOMAL DOMINANT  
UniTrap UNI29978
Vector Insertion
Chr 17: 74738786 - 74751289
Public Clones (sanger) D170E11 (ggtc) IST13898B9 (tigm)
Private Clones not available
Severity of mutation (?) Insertion after 22% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI1234
Vector Insertion
Chr 17: 74751377 - 74755425
Public Clones DD1027 (sanger)
Private Clones OST285817 (lexicon) OST285622 (lexicon) OST176949 (lexicon)
Severity of mutation (?) Insertion after 27% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI13183
Vector Insertion
Chr 17: 74755510 - 74758593
Public Clones CMHD-GT_323B11-3 (cmhd)
Private Clones not available
Severity of mutation (?) Insertion after 31% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI6053
Vector Insertion
Chr 17: 74758690 - 74766587
Public Clones YHD092 (baygenomics) IST11842H10 (tigm)
Private Clones OST500021 (lexicon) OST444554 (lexicon) OST262728 (lexicon)
Severity of mutation (?) Insertion after 37% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI11039
Vector Insertion
Chr 17: 74781381 - 74786373
Public Clones A041A05 (ggtc)
Private Clones not available
Severity of mutation (?) Insertion after 91% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI21244
Vector Insertion
Chr 17: 74786415 - 74787529
Public Clones not available
Private Clones OST337272 (lexicon)
Severity of mutation (?) Insertion after 94% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

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