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Gene ENSMUSG00000024590 (Lmnb1)
Chromosomal location
Chr 18: 56867467 - 56913076 (+)
Description
lamin B1 Gene [Source:MGI (curated);Acc:Lmnb1-001]
RefSeq_dna
NM_010721 
RefSeq_peptide
NP_034851.2 
UniGene
Mm.4105 Mm.457704 
MGI
MGI:96795 
Uniprot/SWISSPROT
P14733 
Uniprot/SPTREMBL
Q8C553 
Human Ortholog
ENSG00000113368 (LMNB1)
Omim 169500 - LEUKODYSTROPHY, DEMYELINATING, ADULT-ONSET, AUTOSOMAL DOMINANT  
UniTrap UNI10639
Vector Insertion
Chr 18: 56868129 - 56888054
Public Clones (sanger) P097A10 (ggtc) D014D06 (ggtc) W175E07 (ggtc) D102G07 (ggtc)
Q016A08 (ggtc) W244B01 (ggtc) W212C06 (ggtc) D106A09 (ggtc) IST13631H2 (tigm)
Private Clones OST279984 (lexicon) OST193073 (lexicon) OST188156 (lexicon) OST173058 (lexicon)
Severity of mutation (?) Insertion after 21% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI2422
Vector Insertion
Chr 18: 56892992 - 56899474
Public Clones AC0463 (sanger) XA130 (baygenomics) XA152 (baygenomics) XB206 (baygenomics)
H004B04 (ggtc)
Private Clones OST45900 (lexicon)
Severity of mutation (?) Insertion after 53% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI851
Vector Insertion
Chr 18: 56899696 - 56900340
Public Clones CF0293 (sanger) (ggtc)
Private Clones OST419964 (lexicon)
Severity of mutation (?) Insertion after 66% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI10964
Vector Insertion
Chr 18: 56902970 - 56907630
Public Clones P134G05 (ggtc) E068C01 (ggtc)
Private Clones not available
Severity of mutation (?) Insertion after 85% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI4324
Vector Insertion
Chr 18: 56909464 - 56912260
Public Clones AG0082 (sanger)
Private Clones OST470561 (lexicon) OST334988 (lexicon) OST23329 (lexicon)
Severity of mutation (?) Insertion after 98% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

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