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Gene ENSMUSG00000026672 (Optn)
Chromosomal location
Chr 2: 4941688 - 4985091 (-)
Description
optineurin Gene [Source:MGI (curated);Acc:Optn-001]
RefSeq_dna
NM_181848 
RefSeq_peptide
NP_862896.1 
UniGene
Mm.401887 Mm.116942 
MGI
MGI:1918898 
Uniprot/SWISSPROT
Q8K3K8 
Uniprot/SPTREMBL
A2ASP3 
Human Ortholog
ENSG00000123240 (OPTN)
Omim 137760 - GLAUCOMA, PRIMARY OPEN ANGLE  606657 - GLAUCOMA, NORMAL TENSION, SUSCEPTIBILITY TO  
UniTrap UNI35362
Vector Insertion
Chr 2: 4975585 - 4984985
Public Clones IST14500C11 (tigm)
Private Clones not available
Severity of mutation (?) Insertion after 0% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI26522
Vector Insertion
Chr 2: 4963567 - 4967032
Public Clones IST12296E8 (tigm) IST10968A6 (tigm) IST11657E5 (tigm) IST14965F6 (tigm)
Private Clones OST113207 (lexicon)
Severity of mutation (?) Insertion after 33% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI23092
Vector Insertion
Chr 2: 4957817 - 4961184
Public Clones not available
Private Clones OST276687 (lexicon) OST249695 (lexicon) OST57924 (lexicon)
Severity of mutation (?) Insertion after 45% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI26936
Vector Insertion
Chr 2: 4948291 - 4952305
Public Clones IST14807D12 (tigm)
Private Clones OST84243 (lexicon)
Severity of mutation (?) Insertion after 80% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI35186
Vector Insertion
Chr 2: 4945112 - 4948291
Public Clones IST12772D7 (tigm)
Private Clones not available
Severity of mutation (?) Insertion after 88% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI28604
Vector Insertion
Chr 2: 4942528 - 4945112
Public Clones not available
Private Clones OST26499 (lexicon)
Severity of mutation (?) Insertion after 93% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

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