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Gene ENSMUSG00000028164 (Manba)
Chromosomal location
Chr 3: 135148578 - 135234293 (+)
Description
mannosidase, beta A, lysosomal Gene [Source:MGI (curated);Acc:Manba-001]
RefSeq_dna
NM_027288 
RefSeq_peptide
NP_081564.3 
UniGene
Mm.280536 Mm.408585 
MGI
MGI:88175 
Uniprot/SWISSPROT
Q8K2I4 
Human Ortholog
ENSG00000109323 (MANBA)
Omim 248510 - MANNOSIDOSIS, BETA A, LYSOSOMAL  
UniTrap UNI7878
Vector Insertion
Chr 3: 135148822 - 135169872
Public Clones RRJ641 (baygenomics) M117C06 (ggtc) D168G02 (ggtc) P075A12 (ggtc)
G014D03 (ggtc) IST12824H11 (tigm) IST12764B10 (tigm) IST11816H11 (tigm)
IST14789A9 (tigm) IST12506B7 (tigm) IST13087H10 (tigm) IST10439B5 (tigm)
IST14780D4 (tigm) IST12651G9 (tigm) IST10657E9 (tigm) IST12239A12 (tigm)
IST10083F10 (tigm) IST11939A10 (tigm) IST11060F7 (tigm) IST12048A2 (tigm)
IST14852E7 (tigm) IST11491H5 (tigm) IST14914F11 (tigm) IST10084A1 (tigm)
IST12754A12 (tigm) IST14870A2 (tigm) IST11302F8 (tigm) IST10935B11 (tigm)
IST10067A4 (tigm)
Private Clones OST214346 (lexicon)
Severity of mutation (?) Insertion after 7% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI26060
Vector Insertion
Chr 3: 135169968 - 135173938
Public Clones IST10106F2 (tigm) IST11742H6 (tigm) IST14820G1 (tigm) IST12633F3 (tigm)
IST11882B5 (tigm) IST10315F9 (tigm) IST14870A2 (tigm) IST12068G12 (tigm)
IST10703H12 (tigm) IST14749D5 (tigm) IST12334B4 (tigm)
Private Clones OST142442 (lexicon)
Severity of mutation (?) Insertion after 10% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI32753
Vector Insertion
Chr 3: 135174045 - 135174766
Public Clones IST13388G5 (tigm)
Private Clones not available
Severity of mutation (?) Insertion after 14% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI11215
Vector Insertion
Chr 3: 135174938 - 135180866
Public Clones G037E08 (ggtc) IST10062C3 (tigm) IST10064C10 (tigm) IST10211A4 (tigm)
IST10433H9 (tigm) IST12930C3 (tigm) IST12228A8 (tigm) IST11849F2 (tigm)
Private Clones OST285991 (lexicon) OST197187 (lexicon) OST191046 (lexicon) OST191017 (lexicon)
Severity of mutation (?) Insertion after 21% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI14507
Vector Insertion
Chr 3: 135180991 - 135185955
Public Clones M125C01 (ggtc) E073D02 (ggtc) FHCRC-GT-S9-5B1 (fhcrc) IST14821B5 (tigm)
IST11151B5 (tigm) IST14447E4 (tigm) IST13148B12 (tigm) IST11526G7 (tigm)
IST12900F3 (tigm) IST13074A1 (tigm) IST10177F6HMF1 (tigm) IST10146C12 (tigm)
IST10154C12 (tigm)
Private Clones OST408564 (lexicon) OST407053 (lexicon) OST388556 (lexicon) OST372252 (lexicon)
OST284891 (lexicon) OST36464 (lexicon)
Severity of mutation (?) Insertion after 26% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI11183
Vector Insertion
Chr 3: 135186132 - 135187480
Public Clones D164E06 (ggtc) D124E06 (ggtc) G042A03 (ggtc) IST12517D4 (tigm) IST10915E11 (tigm)
IST10139E6 (tigm) IST12042B8 (tigm) IST11034D11 (tigm)
Private Clones not available
Severity of mutation (?) Insertion after 32% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI3618
Vector Insertion
Chr 3: 135187592 - 135205275
Public Clones (sanger) BA0198 (sanger) RRF295 (baygenomics) XK329 (baygenomics) XK570 (baygenomics)
P076F05 (ggtc) E048G04 (ggtc) E109E03 (ggtc) E092D08 (ggtc) IST10698G7 (tigm)
IST14767H11 (tigm) IST12341H3 (tigm) IST11825A4 (tigm) IST12744E8 (tigm)
IST10009A10 (tigm) IST12158F9HMF2 (tigm) IST10023F4 (tigm) IST15110H10 (tigm)
IST15098C7 (tigm) IST13285H5 (tigm) IST14968E7 (tigm) IST12922G1 (tigm)
IST11481F4 (tigm) IST11558E1 (tigm) IST11554B7 (tigm) IST14267H3 (tigm)
IST12238B2 (tigm) IST11165E5 (tigm) IST12158F9 (tigm) IST12870G2 (tigm)
IST11689F4 (tigm) IST10338C12 (tigm)
Private Clones OST456810 (lexicon) OST301233 (lexicon) OST274643 (lexicon) OST150933 (lexicon)
OST8729 (lexicon)
Severity of mutation (?) Insertion after 36% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI11267
Vector Insertion
Chr 3: 135205428 - 135207689
Public Clones G077A05 (ggtc) IST12622G3HMF1 (tigm) IST12104H7 (tigm) IST11393B12 (tigm)
Private Clones not available
Severity of mutation (?) Insertion after 42% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI30157
Vector Insertion
Chr 3: 135207808 - 135210513
Public Clones (sanger) D098C04 (ggtc) IST12111C7 (tigm) IST11845D3 (tigm) IST10526C12 (tigm)
IST14721F8 (tigm) IST14999B6 (tigm) IST11074F12 (tigm) IST14779B3 (tigm)
IST12425C5 (tigm) IST10122F7 (tigm) IST10518F8 (tigm) IST11743A10 (tigm)
IST12754D8 (tigm) IST12562G5 (tigm) IST10379F12 (tigm) IST10203C4 (tigm)
IST12984B11 (tigm) IST13368H7 (tigm)
Private Clones not available
Severity of mutation (?) Insertion after 47% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI15484
Vector Insertion
Chr 3: 135210601 - 135212163
Public Clones (sanger) P149B06 (ggtc) D101E11 (ggtc) D065E05 (ggtc) D155E02 (ggtc)
D067B07 (ggtc) PST7322-NR (escells)
Private Clones OST158496 (lexicon) OST132522 (lexicon)
Severity of mutation (?) Insertion after 50% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI9669
Vector Insertion
Chr 3: 135212332 - 135214026
Public Clones (sanger) XG461 (baygenomics) Ex158 (baygenomics) XG655 (baygenomics)
E041A05 (ggtc) P009E10 (ggtc) CMHD-GT_469C11-3 (cmhd) IST14652C12 (tigm)
IST11142A8 (tigm) IST14731A11 (tigm) IST14814E5 (tigm)
Private Clones OST206583 (lexicon) OST36805 (lexicon)
Severity of mutation (?) Insertion after 56% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI1683
Vector Insertion
Chr 3: 135214246 - 135217723
Public Clones CG0593 (sanger) XF345 (baygenomics) E127C04 (ggtc) IST10882C1 (tigm)
IST10951B3 (tigm) IST10252B2 (tigm) IST12286D2 (tigm)
Private Clones not available
Severity of mutation (?) Insertion after 65% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI23144
Vector Insertion
Chr 3: 135217889 - 135226168
Public Clones E098C10 (ggtc) E127C04 (ggtc) (cmhd) CMHD-GT_517C10-5S (cmhd) CMHD-GT_524C10-5S (cmhd)
IST14979B6 (tigm) IST10805H6 (tigm) IST15078G12 (tigm)
Private Clones OST275080 (lexicon) OST43208 (lexicon)
Severity of mutation (?) Insertion after 71% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI24741
Vector Insertion
Chr 3: 135226314 - 135229451
Public Clones D054F06 (ggtc) (ggtc) IST10914E4 (tigm) IST13022D10BBF1 (tigm) IST10585C12 (tigm)
Private Clones OST208340 (lexicon)
Severity of mutation (?) Insertion after 76% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI29884
Vector Insertion
Chr 3: 135229595 - 135230427
Public Clones D186C06 (ggtc) E036C12 (ggtc) IST10782A2 (tigm) IST14995B12 (tigm)
Private Clones not available
Severity of mutation (?) Insertion after 82% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI21187
Vector Insertion
Chr 3: 135230686 - 135233178
Public Clones D186F08 (ggtc) D051H09 (ggtc) D186F07 (ggtc) D186G08 (ggtc) D186E07 (ggtc)
CMHD-GT_387H8-3 (cmhd) (cmhd) IST11231H8 (tigm) IST12326B5 (tigm)
IST12476H3 (tigm) IST10420A12 (tigm) IST11172E8 (tigm) IST14961H2 (tigm)
Private Clones OST339196 (lexicon) OST68518 (lexicon)
Severity of mutation (?) Insertion after 92% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

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