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Gene ENSMUSG00000029009 (Mthfr)
Chromosomal location
Chr 4: 147413192 - 147430317 (+)
Description
5,10-methylenetetrahydrofolate reductase Gene [Source:MGI (curated);Acc:Mthfr-003]
RefSeq_peptide
NP_034970.2 
UniGene
Mm.89959 
MGI
MGI:106639 
Uniprot/SWISSPROT
Q9WU20 
Uniprot/SPTREMBL
A2A7F7 A2A7F9 B2KFL4 B2KFL5 B2KFL6 Q3UDB2 Q3V399 Q497H7 Q8CDE4 Q8CJA5 Q8CJA6 Q8CJA7 
Human Ortholog
ENSG00000177000 (MTHFR)
Omim 236250 - HOMOCYSTINURIA DUE TO DEFICIENCY OF N(5,10)-METHYLENETETRAHYDROFOLATE  601367 - STROKE, ISCHEMIC  601634 - NEURAL TUBE DEFECTS, FOLATE-SENSITIVE  603174 - HOMOCYSTEINEMIA  
UniTrap UNI30136
Vector Insertion
Chr 4: 147413242 - 147415320
Public Clones (sanger) D105G12 (ggtc) IST14581H8 (tigm) IST13020H10 (tigm) IST14499A5 (tigm)
IST12719C10 (tigm) IST11772D9 (tigm) IST11825E2 (tigm)
Private Clones not available
Severity of mutation (?) Insertion after 0% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI14494
Vector Insertion
Chr 4: 147415431 - 147415692
Public Clones FHCRC-GT-S10-3C1 (fhcrc)
Private Clones not available
Severity of mutation (?) Insertion after 5% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI22933
Vector Insertion
Chr 4: 147415692 - 147415939
Public Clones not available
Private Clones OST280911 (lexicon) OST270325 (lexicon) OST80759 (lexicon)
Severity of mutation (?) Insertion after 5% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI850
Vector Insertion
Chr 4: 147427791 - 147429093
Public Clones CF0373 (sanger)
Private Clones not available
Severity of mutation (?) Insertion after 84% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI7370
Vector Insertion
Chr 4: 147429214 - 147429481
Public Clones RRS464 (baygenomics)
Private Clones not available
Severity of mutation (?) Insertion after 90% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

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