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Gene ENSMUSG00000029521 (Chek2)
Chromosomal location
Chr 5: 111269036 - 111303152 (+)
Description
CHK2 checkpoint homolog (S. pombe) Gene [Source:MGI Symbol;Acc:MGI:1355321]
RefSeq_dna
NM_016681 
RefSeq_peptide
NP_057890.1 
UniGene
Mm.279308 Mm.419547 
MGI
MGI:1355321 
Uniprot/SWISSPROT
Q9Z265 
Uniprot/SPTREMBL
Q543W6 
Human Ortholog
ENSG00000183765 (CHEK2)
Omim 176807 - PROSTATE CANCER  259500 - OSTEOGENIC SARCOMA  604373 - CHECKPOINT KINASE 2, S. POMBE, HOMOLOG OF  609265 - LI-FRAUMENI SYNDROME 2  
UniTrap UNI20209
Vector Insertion
Chr 5: 111269068 - 111270224
Public Clones (sanger) IST14553H5 (tigm)
Private Clones OST369526 (lexicon) OST135332 (lexicon) OST62421 (lexicon)
Severity of mutation (?) Insertion after 0% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI5059
Vector Insertion
Chr 5: 111270563 - 111277407
Public Clones YTC536 (baygenomics)
Private Clones OST353885 (lexicon)
Severity of mutation (?) Insertion after 20% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI31096
Vector Insertion
Chr 5: 111289944 - 111292276
Public Clones IST11090C2 (tigm) IST12397B1 (tigm)
Private Clones not available
Severity of mutation (?) Insertion after 56% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI3959
Vector Insertion
Chr 5: 111292377 - 111294540
Public Clones AS0133 (sanger)
Private Clones OST379766 (lexicon)
Severity of mutation (?) Insertion after 62% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI3984
Vector Insertion
Chr 5: 111297113 - 111301045
Public Clones AR0767 (sanger) AR0758 (sanger)
Private Clones not available
Severity of mutation (?) Insertion after 90% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI16304
Vector Insertion
Chr 5: 111301127 - 111302498
Public Clones not available
Private Clones OST463525 (lexicon)
Severity of mutation (?) Insertion after 95% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

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