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Gene ENSMUSG00000043535 (Setx)
Chromosomal location
Chr 2: 28980512 - 29037991 (+)
Description
senataxin Gene [Source:MGI (curated);Acc:Setx-001]
RefSeq_peptide
NP_932150.2 
UniGene
Mm.41867 Mm.404861 Mm.472481 
MGI
MGI:2443480 
Uniprot/SWISSPROT
A2AKX3 
Human Ortholog
ENSG00000107290 (SETX)
Omim 602433 - AMYOTROPHIC LATERAL SCLEROSIS 4, JUVENILE  606002 - SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 1  
UniTrap UNI12416
Vector Insertion
Chr 2: 28981070 - 28981371
Public Clones W059F06 (ggtc)
Private Clones OST356236 (lexicon)
Severity of mutation (?) Insertion after 0% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI23415
Vector Insertion
Chr 2: 28981484 - 28982393
Public Clones P141F04 (ggtc) PST19241-NR (escells)
Private Clones OST260610 (lexicon)
Severity of mutation (?) Insertion after 0% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI22528
Vector Insertion
Chr 2: 28982584 - 28985699
Public Clones not available
Private Clones OST293064 (lexicon) OST135991 (lexicon)
Severity of mutation (?) Insertion after 2% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI31357
Vector Insertion
Chr 2: 28989552 - 28994739
Public Clones IST13430H10 (tigm) IST10909A4 (tigm)
Private Clones not available
Severity of mutation (?) Insertion after 6% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI23684
Vector Insertion
Chr 2: 28995909 - 28999409
Public Clones XE069 (baygenomics) IST13085D3 (tigm)
Private Clones OST249244 (lexicon)
Severity of mutation (?) Insertion after 11% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI12233
Vector Insertion
Chr 2: 29004242 - 29005527
Public Clones A050E08 (ggtc)
Private Clones not available
Severity of mutation (?) Insertion after 66% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI12230
Vector Insertion
Chr 2: 29005628 - 29009457
Public Clones (sanger) A050D08 (ggtc) IST14983B8 (tigm)
Private Clones OST106426 (lexicon)
Severity of mutation (?) Insertion after 67% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

UniTrap UNI5192
Vector Insertion
Chr 2: 29009617 - 29012507
Public Clones YTC154 (baygenomics)
Private Clones not available
Severity of mutation (?) Insertion after 69% of polypeptide chain
Proposed experimental design for vector insertion validation (?)

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